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Pas, D.V.M.; Dubey, J.P.
Fatal toxoplasmosis in sand cats (_Felis margarita_)
2008  Journal of Zoo and Wildlife Medicine (39): 362-369

The sand cat (_Felis margarita_) is a small-sized felid occurring in the United Arab Emirates (UAE). The sand cat captive-breeding program at the Breeding Centre for Endangered Arabian Wildlife in Sharjah, UAE, has until recently been severely compromised by very high newborn mortality rates. Two different pairs of sand cats gave birth, respectively, to one and two litters (with a total of eight kittens) between 1999 and 2006. Seven out of eight kittens died between the third and 21st wk of life. Toxoplasmosis was confirmed as the cause of death in these two litters. Adult cats had high antibody titers to _Toxoplasma gondii _before pregnancy, suggesting that maternal immunity did not protect the kittens against infection with _T. gondii_ and that maternal immunity might not have prevented transplacental transmission of the parasite. This observation contrasts with what is seen in domestic cats. To date, this is the first report on confirmed fatal toxoplasmosis and prevalence of _T. gondii_ in sand cats.

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