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Zheng, D.; Liu, X.; Ma, J.
Patterns of genetic variation within a captive population of Amur tiger _Panthera tigris altaica_
2005  Acta Theriologica (50): 23-30

Eight founders and thirty-one descendants were sampled as the Founder group and the Offspring group respectively from a captive population of Amur tiger _Panthera tigris altaica _Temminck, 1844 for population genetic analysis with RAPD and ISSR markers. Integrated with demographic data during the initial recovery stage, results showed: (1) increasing the population size (N) and the effective population size (Ne) greatly retard lose of genetic variation induced mainly by genetic drift and selection; (2) recombination and admixture could cause the Offspring group (5.711%) and the Founder group (10.383%) to hold different linkage disequilibrium (LD); (3) further Ohta's variance analysis indicated genetic drift (87.3%) and epistatic selection (12.7%) maintained LD in population, whereas GENEDROP analysis supported epistatic selection largely derived from artificial selection of managers; (4) both Tajima's test and Fu's test confirmed the statistic neutrality of genetic markers used, moreover the positive value of Tajima's D (0.090) together with the result that _Ð_ (25.286) was bigger than _Š_ (24.898) revealed the Founder group was admixture population, while the negative Tajima's D value (-0.053) together with the result that _Ð__ _(23.679) was less than _Š_ (23.912) disclosed the Offspring group experienced selective sweep.

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