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O'Brien, S.J.
Genetic and phylogenetic analyses of endangered species
1994  Annual Review of Genetics (28): 467-489

Several reviews have chronicled the application of genetic principles to conservation management and summarized the state of genetic data on the few studied species. The goal here is to review some lessons learned by applying empirical population genetic approaches to define the factors that imperil fragile populations. Both the limitations of the inference and the conclusions reached as a community of conservation scientists are summarized. Several examples will illustrate the synthesis of genetic interpretation with demographic, ecological, and life-history data to draw a cohesive picture of the threatened taxon. Most of the examples are endangered large charismatic carnivore species selected for two reasons. First, large carnivore species occupy the top position of a trophic chain for their ecosystem. They are often highly specialized and provide a sensitive barometer of an ecosystem's condition. Second, charismatic species attract long-term field studies that lay the groundwork for formulating falsifiable ecological and life-history hypotheses.

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