IUCN / SSC Cat Specialist Group - Digital Cat Library |
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| D'Arcy, R. | |
| Chronic kidney disease in non-domestic felids in Australian zoos | |
| 2018 Full Book | |
Using both retrospective data from the combined felid records of ten Australian zoos between 1965 and 2015, and prospective monitoring of felids at Taronga Zoo, Sydney between 2012 and 2015, the key aims of this PhD research were to: 1. determine the prevalence of CKD in the Australian population of non-domestic felids; 2. characterise the clinical signs and progression of disease associated with chronic kidney disease (CKD); 3. determine the longitudinal changes of the main diagnostic indicators of kidney function _i.e. _USG, serum creatinine and urea concentrations, and other biochemical and haematological changes seen in felids with and without CKD; 4. assess the risk factors for CKD in non-domestic felids, 5. describe the histological changes seen in a representative sample of kidney tissue specimens from felids confirmed to have died with CKD, and examine their clinical histories for potential causal agents of observed renal histopathological changes, thereby investigating possible aetiologies for CKD; and 6. evaluate the utility of voided urine as a diagnostic tool for earlier recognition of CKD. |
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