IUCN / SSC Cat Specialist Group - Digital Cat Library |
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| Zamora-Perez, A.; Gomez-Meda, B.C.; Ramos-Ibarra, M.L.; Batista-Gonzalez, C.M.; Luna-Aguirre, J.; Gonzalez-Rodriguez, A.; Rodriguez-Avila, J.L.; Zuniga-Gonzalez, G.M. | |
| Los felinos: Una alternativa en estudios de toxicologia genetica? | |
| 2008 Revista de Biologia Tropical (56): 969-974 | |
The micronuclei (MN) test carry out in peripheral blood is fast, simple, economic and it is used to detect genotoxic environmental agents. MN are fragments of chromosomes or complete chromosomes remaining in the cytoplasm after cell division, which increase when organisms are exposed to genotoxic agents. Therefore, species with the highest values of spontaneous micronucleated erythrocytes (MNE) are the most suitable to be potentials biomonitor of micronucleogenic agents, using a drop of blood. Nine species of Felines that present spontaneous MNE in peripheral blood are shown. From these species, the cat has been previously proven, with positive results and also lion (_Panthera leo_), yaguaroundi (_Felis yagoaroundi_), lynx (_Lynx ruffus_), jaguar (_Panthera onca_), puma (_Puma concolor_), tiger (_Panthera tigris_), ocelote (_Felis padalis_) and leopard (_Panthera pardus_) display spontaneous MNE, and with this characteristic this Family can be propose like a potential group to be used in toxicogenetic studies. |
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